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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of MALAT1
ncRNA name MALAT1
ncRNA Category lncRNA
ID 378938
Ensembl ENSG00000251562
Synonyms HCN, LINC00047, MALAT-1, NCRNA00047, NEAT2, PRO1073, mascRNA
Disease name proliferative vitreoretinopathy (PVR)
Species Homo sapiens
Tissues/Cell_line PVR vitreous samples; human RPE cell line ARPE-19; human primary RPE cells
Methods qRT-PCR, Western blot, immunofluorescence, transwell assay
Expression pattern up-regulated
Functional description LncRNA MALAT1 is involved in TGFβ1-induced EMT of human RPE cells and provides new understandings for the pathogenesis of PVR.
PubMed ID 27019196
Year 2016
Title Long Non-Coding RNA MALAT1 Mediates Transforming Growth Factor Beta1-Induced Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells.
Drug-related ncRNA NO

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